Acute Retinal Necrosis Syndrome

Acute Retinal Necrosis Syndrome (ARN Syndrome; Bilateral Acute Retinal
Necrosis; Barn Syndrome)                                    27

General: Evidence of association with herpes-type deoxyribonucleic acid (DNA) virus; occurs both unilaterally and bilaterally; includes varicella-zoster virus and herpes simplex virus type 1.

Ocular: Uveitis; vasculitis; vitreitis; retinal detachment; vitreous opacification; retinal periarteritis; exudates of peripheral retina; retinal necrosis; optic nerve enlargement; papillitis; arcuate neuroretinitis; arteritis and phlebitis (affecting the retinal vasculature); necrotizing retinitis; moderate to severe vitreitis; anterior segment inflammation; optic neuritis; late retinal detachment.

Clinical: None.

Culbertson WW, et al. Chickenpox-associated acute retinal necrosis syndrome. Ophthalmology 1991; 98:1641-1645.

Culbertson WW, et al. Varicella zoster virus is a cause of the acute retinal necrosis syndrome. Ophthalmology 1986; 93:559-567.

Duker JS, Blumenkranz MS. Diagnosis and management of the acute retinal necrosis syndrome (ARN) syndrome. Surv Ophthalmol 1991; 35:327-343.

Falcone PM, Brockhurst RJ. Delayed onset of bilateral acute retinal necrosis syndrome: a 34-year interval. Ann Ophthalmol 1993; 25:373-374.

Fisher JP, et al. The acute retinal necrosis syndrome. Part 1: clinical manifestations. Ophthalmology 1982; 89: 1309-1316.

Margolis T, et al. Acute retinal necrosis syndrome with papillitis and arcuate neuroretinitis. Ophthalmology 1988; 95: 937-940.

Peyman GA, et al. Vitrectomy and intravitreal antiviral drug therapy in acute retinal necrosis syndrome. Arch Ophthalmol 1984; 102:1618-1621.

Thompson WS, et al. Acute retinal necrosis caused by reactivation of herpes simplex virus type 2. Am J Ophthalmol 1994; 118:205-211.