Addison Syndrome

Addison Syndrome (Addison Disease; Idiopathic Hypoparathyroidism;
Adrenal Cortical Insufficiency; Moniliasis-Idiopathic Hypoparathyroidism) 29

General: Familial occurrence; association with moniliasis; onset during end of first and beginning of second decade of life; atrophy of adrenal cortex; prognosis for life is poor, with death in adrenal crisis.

Ocular: Ptosis; blepharitis; blepharospasm; keratoconjunctivitis with extreme photophobia; corneal ulcers; episcleritis; keratitic moniliasis; cataracts; papilledema.

Clinical: Moniliasis; tetany; progressive weakness; anorexia; progressive skin pigmentation; dry skin; brittle fingernails and toenails; sparse pubic and axillary hair or total alopecia; impotence.

Addison T. On the constitutional and local effects of disease of the suprarenal capsules. London S. Highley: Lend. Med. Gaz., 1949; 43:517.

Collins JF. Handbook of clinical ophthalmology. New York: Masson, 1982:229.

Gass JD. The syndrome of keratoconjunctivitis, superficial moniliasis, idiopathic hypoparathyroidism and Addison's disease. Am J Ophthalmol 1962; 54:660.

Magalini SI, Scrascia E. Dictionary of medical syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.

Williams GH, Dluhy RG. Diseases of the adrenal cortex. In: Isselbacher KJ, et al., eds. Harrison’s principles of internal medicine, 13th ed. New York: McGraw-Hill, 1994:1953-1975.