Agranulocytosis Syndrome
Agranulocytosis Syndrome (Pernicious Leukopenia Syndrome; Schultz
Syndrome; Agranulocytic Angina Syndrome; Malignant Neutropenia
Syndrome) 33
General: Caused by hypersensitivity reaction to chemicals, drugs, and ionizing radiation; may be idiopathic; more frequent in adults; female (3:1) preponderance; acute onset.
Ocular: Scleral and conjunctival icterus; conjunctival hemorrhages; retinal hemorrhages.
Clinical: Swollen, painful joints; malaise; sore throat with mucous membrane ulceration; sepsis.
Magalini SI, Scrascia E. Dictionary of medical syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.
McCluskey HB. Corticotropin (ACTH) in treatment of agranulocytosis following sulfisoxazole therapy. JAMA 1953; 152:232.
Schultz W. Uber Eigenartige Halserkrankungen. Dtsch Med Wochenschr 1922; 48: 1495.
Syndrome; Agranulocytic Angina Syndrome; Malignant Neutropenia
Syndrome) 33
General: Caused by hypersensitivity reaction to chemicals, drugs, and ionizing radiation; may be idiopathic; more frequent in adults; female (3:1) preponderance; acute onset.
Ocular: Scleral and conjunctival icterus; conjunctival hemorrhages; retinal hemorrhages.
Clinical: Swollen, painful joints; malaise; sore throat with mucous membrane ulceration; sepsis.
Magalini SI, Scrascia E. Dictionary of medical syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.
McCluskey HB. Corticotropin (ACTH) in treatment of agranulocytosis following sulfisoxazole therapy. JAMA 1953; 152:232.
Schultz W. Uber Eigenartige Halserkrankungen. Dtsch Med Wochenschr 1922; 48: 1495.



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