Friday, March 16, 2007

Conjunctivitis, Ligneous

Conjunctivitis, Ligneous

General: Autosomal recessive; palpebral conjunctiva becomes the site of dense woody membrane that has global shape; associated with systemic use of tranexamic acid.

Ocular: Corneal scarring; dense membrane of the conjunctiva; may occur as a complication following strabismus surgery.

Clinical: None.

Bierly JR, et al. Ligneous conjunctivitis as a complication following strabismus surgery. J Pediatr Ophthalmol Strabismus 1994; 31:99-103.

Diamond JP, et al. Tranexamic acid-associated ligneous conjunctivitis with gingival and peritoneal lesions. Br J Ophthalmol 1991; 75:753-754.

McKusick VA. Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders, 12th ed. Baltimore: The Johns Hopkins University Press, 1998.

Online Mendelian Inheritance in Man, OMIM. McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University and National Center for Biotechnology Information, National Library of Medicine, February 12, 2007. World Wide Web URL: http://www.ncbi.nlm.nih.gov/omim/.

Pavan-Langston D. Cornea and external disease. Ligneous conjunctivitis. In: Pavan-Langston D, ed. Manual of Ocular Diagnosis and Therapy, 4th ed. Boston: Little, Brown and Company, 1995:103.

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