Felty Syndrome
Felty Syndrome (Chauffard-Still Syndrome; Primary Splenic Neutropenia with Arthritis; Rheumatoid Arthritis with Hypersplenism; Still-Chauffard Syndrome; Uveitis-Rheumatoid Arthritis Syndrome)
General: Etiology not fully understood, possibly infection or allergy; onset in middle-aged patients or children; prognosis poor; collagen disorder; occasionally can occur without articular disease.
Ocular: Decreased tear formation; scleromalacia perforans; keratoconjunctivitis; chronic anterior uveitis; scleritis; vitreous opacities; macular edema; choroidal inflammation; papillitis; keratitic precipitates; band-shaped keratopathy.
Clinical: Rheumatoid arthritis; splenomegaly; leukopenia; anemia (mild); oral lesion with ulcers and atrophy.
Crosby WH. What to treat in Felty's syndrome. JAMA 1973; 225:1114.
Davis M. Endogenous uveitis in children: associated band-shaped keratopathy and rheumatoid arthritis. Arch Ophthalmol 1953; 50:443.
Felty AR. Chronic arthritis in the adult associated with splenomegaly and leukopenia. Bull Johns Hopkins Hosp 1924; 35:16.
Pau H. Differential diagnosis of eye disease. New York: Thieme, 1987.
Reddy CV, Foster CS. Adult rheumatoid arthritis. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology, vol. V. Philadelphia: WB Saunders, 1994:2889.
General: Etiology not fully understood, possibly infection or allergy; onset in middle-aged patients or children; prognosis poor; collagen disorder; occasionally can occur without articular disease.
Ocular: Decreased tear formation; scleromalacia perforans; keratoconjunctivitis; chronic anterior uveitis; scleritis; vitreous opacities; macular edema; choroidal inflammation; papillitis; keratitic precipitates; band-shaped keratopathy.
Clinical: Rheumatoid arthritis; splenomegaly; leukopenia; anemia (mild); oral lesion with ulcers and atrophy.
Crosby WH. What to treat in Felty's syndrome. JAMA 1973; 225:1114.
Davis M. Endogenous uveitis in children: associated band-shaped keratopathy and rheumatoid arthritis. Arch Ophthalmol 1953; 50:443.
Felty AR. Chronic arthritis in the adult associated with splenomegaly and leukopenia. Bull Johns Hopkins Hosp 1924; 35:16.
Pau H. Differential diagnosis of eye disease. New York: Thieme, 1987.
Reddy CV, Foster CS. Adult rheumatoid arthritis. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology, vol. V. Philadelphia: WB Saunders, 1994:2889.
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