Monday, March 26, 2007

Foster Kennedy Syndrome

Foster Kennedy Syndrome (Basal-Frontal Syndrome; Gowers-Paton-Kennedy Syndrome)

Caused by tumor in base of frontal lobe or sphenoidal meningioma.

Ocular: Central scotoma may be present on side of optic atrophy; enlarged blind spot and peripheral contraction of field (opposite eye); homolateral descending optic atrophy due to compression of the ipsilateral optic nerve at the optic foramen; contralateral papilledema due to increased intracranial pressure; ipsilateral proptosis.

Clinical: Anosmia; headache; dizziness; vomiting; memory loss; psychic changes; also may be caused by an olfactory groove tumor (usually a meningioma) or pituitary adenoma.

Banerjee T, Meagher JN. Foster Kennedy syndrome, aqueductal stenosis and empty sella. Am Surg 1974; 40:552.

Kennedy F. Retrobulbar neuritis as an exact diagnostic sign of certain tumors and abscesses in frontal lobes. Am J Med Sci 1911; 142:355.

Ruben S, et al. Pituitary adenoma presenting as the Foster-Kennedy syndrome. Br J Ophthalmol 1992; 76:117-119.

Yildizhan A. A case of Foster Kennedy syndrome without frontal lobe or anterior cranial fossa involvement. Neurosurg Rev 1992; 15:139-142.


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