Lymphoid Hyperplasia

Lymphoid Hyperplasia (Reactive Lymphoid Hyperplasia; Lymphoid Tumors; Malignant Lymphoma; Pseudolymphoma; Pseudotumor; Burkitt Lymphoma; Neoplastic Angioendotheliomatosis) 753

General: Occurs in tropical Africa; young children; idiopathic orbital inflammation; systemic disease is rarely associated but occasionally occurs with either vasculitis or lymphomas; etiology of Burkitt lymphoma currently includes three factors: (i) Epstein-Barr virus, (ii) malaria, and (iii) chromosomal translocations activating the c-myc oncogene, which induces uncontrolled B-cell proliferation.

Ocular: Proptosis; extraocular motility disturbances; lesions of orbit, lacrimal gland, conjunctiva, and uvea; cortical blindness; retinal artery occlusion; retinal vascular and pigment epithelial alterations; vitreitis.

Clinical: Maxillary tumor; Epstein-Barr virus; cranial neuropathy.

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