Friday, March 10, 2006

Glossary and Index 154

Selenium: A trace mineral that is important in the function of the anti-oxidant enzyme, glutathione-peroxidase. Selenium is often included in vitamins for the eye but its value is unknown and there is a risk of toxicity if too much is taken; 39, 53, 55.

Smoking; 20, 21, 28, 29, 32, 36, 42, 44, 56.

Statin drugs: A large family of cholesterol-lowering drugs that may reduce the risk of AMD; 50, 57

Sunlight: And its affect on AMD; 30.

Subretinal Surgery Study (SST): A randomized controlled trial which showed no visual benefit of surgery in the wet form of AMD; 88.

Toll-like receptor: Defects in genes that code for this receptor have been found to be associated with AMD. The receptor is important for the functioning of macrophages which are involved in the removal of foreign matter from the body. The receptor also helps to remove the spent outer segments of cone cells so that they can be renewed; 20.

Thermal laser: A procedure wherein a strong laser beam is absorbed by pigment mainly in the RPE and converted to heat causing a destructive burn; 63.

Trans fats: Artificially hydrogenated vegetable oils that are bad for your eyes and heart. They are often found in margarine and other processed foods; 46.

Transpupillary thermal therapy (TTT): A treatment for neovascular AMD that involves slowly heating the abnormal vessels with an infrared laser. TTT has been replaced by more effective treatments; 81.

Triamcinolone acetonide: The generic name for KenalogĀ®.

Vascular endothelial growth factor (VEGF): A polypeptide that stimulates the growth of choroidal neovascularization in AMD; 69.

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